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Lai, H. H., Chiu, C. H., Kong, M. S., Chang, C. J., & Chen, C. C. (2019). Probiotic Lactobacillus casei: Effective for Managing Childhood Diarrhea by Altering Gut Microbiota and Attenuating Fecal Inflammatory Markers. Nutrients, 11(5), 1150. https://doi.org/10.3390/nu11051150
Tormo Carnicer, R., Infante Piña, D., Roselló Mayans, E., & Bartolomé Comas, R. (2006). Efecto de la ingesta de leche fermentada con Lactobacillus casei DN-114 001 sobre la flora intestinal [Intake of fermented milk containing Lactobacillus casei DN-114 001 and its effect on gut flora]. Anales de pediatria (Barcelona, Spain : 2003), 65(5), 448–453. https://doi.org/10.1157/13094251
References
Cincinnati Children’s Hospital, Use of Lactobacillus rhamnosus GG in children with acute gastroenteritis; 2011
Falagas, M. E., G. I. Betsi, et S. Athanasiou. 2007. « Probiotics for the Treatment of Women with Bacterial Vaginosis ». Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 13(7): 657‑64.
Happy Tummy Consortium, Lavalle, L., Sauvageot, N., Cercamondi, C. I., Jankovic, I., Egli, D., & Vandenplas, Y. (2023). Limosilactobacillus reuteri DSM 17938-Containing Infant Formulas and the Associations with Gastrointestinal Tolerance: A Cross-Sectional Observational Study. Nutrients, 15(3), 530. https://doi.org/10.3390/nu15030530
Horvath et al., Meta-analysis: Lactobacillus rhamnosus GG for abdominal pain-related functional gastrointestinal disorders in childhood; Aliment Pharmacol Ther 2011; 33: 1302–1310.
Neyrinck, Audrey M. et al. 2021. « Improvement of Gastrointestinal Discomfort and Inflammatory Status by a Synbiotic in Middle-Aged Adults: A Double-Blind Randomized Placebo-Controlled Trial ». Scientific Reports 11(1): 2627.
Pacha-Herrera, D., Erazo-Garcia, M. P., Cueva, D. F., Orellana, M., Borja-Serrano, P., Arboleda, C., Tejera, E., & Machado, A. (2022). Clustering Analysis of the Multi-Microbial Consortium by Lactobacillus Species Against Vaginal Dysbiosis Among Ecuadorian Women. Frontiers in cellular and infection microbiology, 12, 863208. https://doi.org/10.3389/fcimb.2022.863208
Salinas A. M., Osorio V. G., Endara P. F., Salazar E. R., Vasco G. P., Vivero S. G., et al. (2018). Bacterial Identification of the Vaginal Microbiota in Ecuadorian Pregnant Teenagers: An Exploratory Analysis. PeerJ 6, e4317. doi: 10.7717/peerj.4317
Seddik, Hamza Ait et al. 2017. « Lactobacillus Plantarum and Its Probiotic and Food Potentialities ». Probiotics and Antimicrobial Proteins 9(2): 111‑22.
Uchida K. et al., Effect on fermented milk containing Bifidobacterium lactisBb-12 on stool frequency, defecation, fecal microbiota and safety of excessive ingestion in healthy female students – 2nd report- 2005
Vujic, Goran, Alenka Jajac Knez, Vedrana Despot Stefanovic, et Vedrana Kuzmic Vrbanovic. 2013. « Efficacy of Orally Applied Probiotic Capsules for Bacterial Vaginosis and Other Vaginal Infections: A Double-Blind, Randomized, Placebo-Controlled Study ». European Journal of Obstetrics and Gynecology and Reproductive Biology 168(1): 75‑79.
Wu, Z., Xu, Q., Gu, S., Wang, Q., Chen, Y., Lv, L., Zheng, B., Wang, K., Wang, S., Xia, J., & Li, L. (2022). Modulation of Lactobacillus rhamnosus GG on the gut microbiota and metabolism in mice with Clostridioides difficile infection. Food & function, 13(10), 5667–5679. https://doi.org/10.1039/d2fo00374k
Zhou, B., Jin, G., Pang, X., Mo, Q., Bao, J., Liu, T., Wu, J., Xie, R., Liu, X., Liu, J., Yang, H., Xu, X., Wang, B., & Cao, H. (2022). Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood. Pharmacological research, 177, 106090. https://doi.org/10.1016/j.phrs.2022.106090
Woman’s Health
This premix contains 3 strains that work towards maintaining the equilibrium of the feminine flora. The link between the maintenance of a healthy vaginal flora and the presence of lactobacilli has been established for a long time (Butler et al., 1960).
Bacterial vaginosis is the most common vaginal infection in reproductive-age women (Kairys et al., 2022). Therefore maintaining a good amount of Lactobacilli in the feminine flora appears to be mandatory to avoid bacterial vaginosis. Our lactogyn premix aims in that direction by including three different strains of lactobacilli: L. acidophilus, L. brevis and L. crispatus that were identified as having a high colonization capacity of the vagina. They have a good adherence to the vaginal epithelial cells, produce H2O2 and therefore their combined action counteracts the adhesion/colonization of pathogens.
This premix has been studied in a phase 2 randomized (1:1 allocation ratio) interventional parallel group prospective placebo controlled multicenter clinical study. The results were extremely positive as the recurrence of bacterial vaginosis was two times lower in the group taking Lactogyn premix compared to the placebo group.
Intestinal flora’s health for infants
This premix contains 4 strains of bifidobacterial and 1 strain of lactobacillus for a total of 5 different strains.
The intestinal flora of the new-born baby develops in the first moments which follow the birth. Mode of childbirth, type of food (feeding-bottle or breast feeding), taken antibiotics, environment… are as many factors which influence the development of this intestinal flora. Any disturbance of the normal development of the intestinal flora can be the cause of various disorders.
Giving probiotics to new-born or infants/childs is advised and even more in case of diarrhea, colic and irritable bowel syndrome.
Intestinal flora’s health.
This premix contains 2 strains that work toward maintaining the equilibrium of the gut’s flora and preventing some symptoms.
Lacticaseibacillus rhamnosus has been studies in case of acute diarrhoea and antibiotic-associated diarrhoea and has been identifies as effective in reducing duration of acute diarrhoea in children and adults, and its effect depends on the dose administered and the timing of initiation of the treatment (the earlier, the better). The effect is highly significant among patients with watery diarrhoea and viral gastroenteritis. (Cincinnati ,2011)
This strain has also showed good results in reducing the abdominal pain particularly associated with irritable bowel syndrome (Horvath,2011).
On its part, Bifidobacterium animalis subsp lactis has also be studied in the case of antibiotics-associated diarrhoea with significant result in reducing the duration. A clinical study also proven that associated with a prebiotic, number of days with abdominal discomfort was significantly decreased in the group treated with the symbiotic. More persons taking the symbiotic reported a significantly or much improved perception of change about their transit. (Neyrinck et al., 2021)
This premix is therefore advised in case of treatment with antibiotics in order to restore the gut’s flora equilibrium and to reduce the diarrhoea that might be associated with the treatment. It allows also to relieve from intestinal discomfort.
Intestinal flora’s health.
This premix contains 3 strains strains that work toward maintaining the equilibrium of the gut’s flora and preventing some symptoms.
In addition to this two strains mentioned in Forte Premix (2 strains), L. plantarum has been added to this premix as it has also been studied with promising results on Irritable Bowel Syndrome and its capability of reducing its symptoms. (Seddik et al., 2017). Moreover, L. plantarum is also capable to produce bacteriocins that are extracted to be used a biopreservatives in foods and could therefore be used in fighting pathogens in the gut. (Behera et al., 2018)
Immunity health
This blend contains 3 strains specifically chosen for their effect on the enhancement of the immune system response.
These three specifics strains have demonstrated positive results on the immune response in diverse studies. This blend is recommended to be used to improve the immune response directly from the gut.
IBS Health
This blend contains 5 strains specifically chosen for their action on the intestinal transit and their anti-constipation function.
A lot of articles and studies on these strains are oriented to the bowel movements with positive results. This is why this blend is recommended to be used for any discomfort, bloating, or digestive trouble.
Intestinal flora’s health and digestion
This blend of 4 strains has been developped to relieve form intestinal discomfort.
These strains together work towards a better intestinal comfort by reducing abdominal pain, adjusting the stool frequency and reducing IBS symptoms.
These different strains have proven their efficacy on inhibition of clositridum difficile that could induce diarrhoea.
Moreover they also have proven to their efficacy on the transit, their action on acute diarrhoae or antiobiotic-associated diarrhoea.
This blend has been designed toward senior who are more sensitive to antiobiotic-associated diarrhoea.
This blend is advised for preventing diarrhea associated to antiobiotcs, viral and bacterial diarrhea.
We offer women a range of food supplements, rich in vitamins and omega. Discover our Vinalac products adapted to the specific needs of women during pregnancy and breastfeeding. Or our Fémina range, which strengthens the vaginal flora and increases the resistance of the urinary tract. Strengthen your immunity, prepare for the wish to be pregnant, contribute to the development of your child.
